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Trials designed to inform clinical practice in the real world are known as pragmatic trials. They are often described by their focus on practical aspects of study design, including the recruitment process and consent, adhering and the use of standard equipment.

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Another example of a practical trial is the Home Blood Pressure Management (HBPM) study, which employed a variety of investigators and had participants from different geographic areas. This type of heterogeneity is essential for pragmatic trials to be able to prove their validity and also helps to reduce bias in the results. Too much heterogeneity, however could cause issues with the design of the trial.

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The purpose of pragmatic trials is to replicate real-life scenarios and to achieve maximum credibility externally. They are typically commissioned by practitioners and policy makers to inform their decision making. They are also a good way to identify the causality between the intervention and its effects. However, they should not be used to replace explanatory studies.

The concept of pragmatism is controversial, and there are questions about whether pragmatic trials should be used to replace explanation tests or if they should be an addition to them. Schwartz and 프라그마틱 슬롯 체험 Lellouch1 suggested the distinction between explanation trials, which prove the clinical or physiological hypothesis as well as pragmatic trials, which guide policy and practice decisions. They also proposed an approach to pragmatic trials, which they called PRECIS.2 This tool was designed to define the characteristics of a pragmatic study which includes the recruitment process, the design and implementation of the intervention, as well as follow-up.

The number of pragmatic trials is growing. A recent Medline search using the keywords naturalistic and 프라그마틱 슬롯 사이트 pragmatic, which was limited to controlled trials that are randomized (RCTs) produced 34 articles, as shown in red in Figure 2. This indicates that the health sciences community is becoming more acquaint to the issue of pragmatism. It is important to keep in mind, however, that the majority of studies were conducted in primary care settings.